Can the current generation quantum computers solve science problems that conventional computers cannot? The jury is still out on this, but key to achieving this goal is the ability to perform robust quantum computation on near-term hardware. In this talk, I will describe three different types of robust computation that we have successfully completed: (i) computing topological properties (ii) simulating driven-dissipative systems and (iii) performing coherent time evolution with constant depth circuits. I will describe the techniques needed for robust computation, and will show results, such as time evolution with 1000 Trotter steps, running more than an order of magnitude longer than the decoherence time of the machine. I will end with a discussion on how one can directly measure nonequilibrium Green’s functions and how this can usher in a new era in simulations of pump-probe experiments.